Creighton vs Gonzaga Gonzaga v. Creighton Game Preview: Jay walking The Zags are looking to pick up the Omaha double in one weekend with a win over Creighton after securing Hunter Sallis’ commitment. NCAA Tournament Sweet 16: (1) Gonzaga (28-0) vs (5) Creighton (22-8) prediction and college basketball game preview. Gonzaga vs Creighton Game Preview For latest lines and to bet on college basketball, go to BetMGM The Creighton Bluejays will take on a giant killer role on Sunday when they meet the Gonzaga Bulldogs in a Sweet 16 matchup in the West Region. Creighton is the No. 5 seed, advancing with wins over UC Santa Barbara and Ohio last week. Gonzaga is the No. 1 overall seed in the 2021 NCAA Tournament field, with breezy wins over Norfolk State and Oklahoma. The Bulldogs (28-0) maintain an undefeated record and are in search of the first perfect season in Division 1 men's basketball since the Indiana Hoosiers in 1976. Tip-off is at 2:10 p.m. ET on CBS from Hinkle Fieldhouse. William Hill Sportsbook lists the Bulldogs 13-point favorites, while the over-under, or total number of points Vegas thinks will be scored, is 158.5 in the latest Gonzaga vs. Creighton odds. Before making any Creighton vs. Gonzaga picks, check out the college basketball predictions and betting advice from the SportsLine Projection Model. The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns. Now, the model has set its sights on Gonzaga vs. Creighton in the Sweet 16 of the NCAA Tournament 2021. You can head to SportsLine to see its picks. Here are several college basketball odds and trends for Creighton vs. Gonzaga: Gonzaga vs. Creighton spread: Gonzaga -13 Gonzaga vs. Creighton over-under: 158.5 points Gonzaga vs. Creighton money line: Gonzaga -1100, Creighton +700 ZAG: The Bulldogs are 6-4 against the spread in the last 10 games CRE: The Bluejays are 6-4 against the spread in the last 10 games Why Gonzaga can cover Gonzaga is the best offensive team in the country, and the Bulldogs have three legitimate stars to lead the charge. Corey Kispert is the WCC Player of the Year and a first team All-American, averaging 19.2 points per game with blistering shooting numbers. Kispert converts 54.5 percent of his shots, including 45.8 percent from 3-point range, and he is also a 90 percent free throw shooter. Drew Timme and Jalen Suggs were both first team All-WCC selections, with Timme averaging 18.8 points and 7.3 rebounds per game and Suggs adding 14.1 points, 5.3 rebounds, 4.3 assists and 2.0 steals per contest. As a team, Gonzaga leads the country in scoring, both on a per-game and per-possession basis, and the Zags are difficult to defend. In this matchup, they can also take solace in some weaknesses from Creighton. The Bluejays struggle to create turnovers defensively, and they are one of the worst free throw shooting teams in the country, ranking outside the top 300 at 64.3 percent. Creighton is also well below-average in both offensive rebounding and free throw creation, giving Gonzaga the edge in the possession battle. Why Creighton can cover Creighton isn't quite as talented as Gonzaga in an overall sense, but the Bluejays do have a top-tier contributor in junior guard Marcus Zegarowski. The veteran has a penchant for making big plays in big moments, and Zegarowski was a first team All-Big East selection in 2020-21. He is averaging 15.7 points and 4.4 assists per game this season, including a 20-point showing against Ohio, and Zegarowski is a knock-down shooter, converting 42.1 percent of his 3-point attempts. The Bluejays should be able to score effectively, even against a top-10 defense in Gonzaga. Creighton was No. 2 in the Big East in offensive efficiency, with elite shooting metrics, and the Bulldogs do have a notable weakness in rim protection. Gonzaga has only a 7.0 percent block rate, which ranks 250th in the country this season. How to make Creighton vs. Gonzaga picks The model is leaning over on the total, projecting the teams to combine for 162 points. It also says one side of the spread hits almost 60 percent of the time. You can only see the pick at SportsLine. So who wins Creighton vs. Gonzaga? And which side of the spread hits almost 60 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.