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Gonzaga vs. Creighton odds: 2021 NCAA Tournament picks, March Madness Sweet 16 predictions from proven model Gonzaga vs. Creighton odds, picks, predictions for March Madness Sweet 16 game Gonzaga vs Creighton Prediction, Game Preview: NCAA Tournament Sweet 16 Gonzaga vs Creighton live stream: How to watch March Madness online March Madness: Gonzaga vs. Creighton odds, picks and prediction Gonzaga v. Creighton Game Preview: Jay walking Mark Few and the Gonzaga Bulldogs take the floor in a Sweet 16 matchup on Sunday afternoon. The undefeated No. 1 seed will face the No. 5 seed Creighton Bluejays in the first 2021 NCAA Tournament game of the day. Creighton advanced to this point without beating a single-digit seed, knocking off No. 12 UC Santa Barbara and No. 13 Ohio during the first weekend. Gonzaga cruised past No. 16 seed Norfolk State and No. 8 seed Oklahoma to reach the Sweet 16. Tip-off is at 2:10 p.m. ET on CBS from Hinkle Fieldhouse. William Hill Sportsbook lists the Bulldogs 13.5-point favorites, while the over-under, or total number of points Vegas thinks will be scored, is 158.5 in the latest Gonzaga vs. Creighton odds. Before making any Creighton vs. Gonzaga picks, check out the college basketball predictions and betting advice from the SportsLine Projection Model. The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns. The Gonzaga vs Creighton live stream is today, and it could be another step towards a perfect season for the Bulldogs. And the Blue Jays? Well, they look to be the spoiler in this March Madness live stream. If you haven’t heard yet, here it is: The Gonzaga Bulldogs (28-0) are trying to do something that hasn’t been done since 1976. That “something” is become the first undefeated national champion since Bobby Knights’ ’76 Hoosiers. So far, the Zags have smoked #16 Norfolk, then easily handled #8 Oklahoma. Now they face #5 Creighton in the Sweet 16. Now, the model has set its sights on Gonzaga vs. Creighton in the Sweet 16 of the NCAA Tournament 2021. You can head to SportsLine to see its picks. Here are several college basketball odds and trends for Creighton vs. Gonzaga: Gonzaga fans will be fairly familiar with the Bulldogs’ Sweet 16 opponent in the Creighton Bluejays. After all, these teams recently played a home-and-home series during the 2017-18 and 2018-19 seasons in which the Zags won both games and averaged 97 ppg in doing so. The Creighton Bluejays are making their first appearance in the Sweet 16 since 1974, and their first advancing to this point in the tournament in the modern era so this is fairly uncharted territory for the program. To get to the second weekend, Creighton beat a pair of double-digit seeds in UC Santa Barbara (63-62) before comfortably dispatching the Ohio Bobcats 72-58. When what some people prefer to call the “new Big East” was formed in advance of the 2013-14 season – mostly, that’s a term used by people who spent a lot of time around the “old Big East – there was some discussion regarding whether it would be prudent to invite Gonzaga to join. Gonzaga is one of the best basketball programs in any conference. The Zags would have been a prize for the Big East. But however big the Big East might be, it probably was a stretch to attempt to annex Spokane, Wash. So instead we get Gonzaga vs. Creighton in the NCAA Tournament Sweet 16. Gonzaga enters as the No. 1 overall seed in the tournament, still carrying an undefeated record, and Creighton arrives having defeated two mid-major opponents after losing by a boatload of points in the Big East Tournament final. So we don’t know if the Blue Jays have repaired all that went wrong in the championship game against Georgetown. They beat two fine teams, UC Santa Barbara and Ohio U., but neither presents the sort of challenge that arrives in Gonzaga uniforms. The Zags are the best team in the country. Whether they will be champions will be decided in four games. Or fewer. Here's everything to know about betting on Gonzaga vs. Creighton in the 2021 NCAA Tournament, including updated odds, trends and our expert's prediction for the Sweet 16 game. Why Gonzaga can cover Gonzaga is the best offensive team in the country, and the Bulldogs have three legitimate stars to lead the charge. Corey Kispert is the WCC Player of the Year and a first team All-American, averaging 19.2 points per game with blistering shooting numbers. Kispert converts 54.5 percent of his shots, including 45.8 percent from 3-point range, and he is also a 90 percent free throw shooter. Drew Timme and Jalen Suggs were both first team All-WCC selections, with Timme averaging 18.8 points and 7.3 rebounds per game and Suggs adding 14.1 points, 5.3 rebounds, 4.3 assists and 2.0 steals per contest. As a team, Gonzaga leads the country in scoring, both on a per-game and per-possession basis, and the Zags are difficult to defend. In this matchup, they can also take solace in some weaknesses from Creighton. The Bluejays struggle to create turnovers defensively, and they are one of the worst free throw shooting teams in the country, ranking outside the top 300 at 64.3 percent. Creighton is also well below-average in both offensive rebounding and free throw creation, giving Gonzaga the edge in the possession battle. Why Creighton can cover Creighton is one of the best offensive teams in the nation, including the No. 2 mark in offensive efficiency during Big East play. The Bluejays led their conference in both 2-point shooting (55.8 percent) and overall shooting efficiency, and Creighton is a top-10 team in the country inside the arc. The Bluejays are also well above-average in 3-point shooting at 36.5 percent, including a 42.1 percent clip for All-Big East guard Marcus Zegarowski. Creighton takes care of the ball, committing a turnover on only 15.8 percent of possessions, and generating quality shots will be key against Gonzaga. On the other end, the Bulldogs are tremendous offensively, but Creighton has solidly above-average metrics in adjusted defensive efficiency, effective field goal percentage allowed (46.4 percent), block rate (9.2 percent), steal rate (9.9 percent) and free throw prevention. The Bluejays also played a tougher strength of schedule this season, and they are battle tested in a tournament setting after two competitive games. How to make Creighton vs. Gonzaga picks The model is leaning over on the total, projecting the teams to combine for 162 points. It also says one side of the spread hits almost 60 percent of the time. You can only see the pick at SportsLine.